Identification and characterization of an excipient from natural sources is an alternative approach in formulation development. The present study was carried out to extract starch from Lentil and to evaluate its binding property in tablets using ketoprofen as model drug. Starch extraction was carried out using acetone to precipitate starch. Formulations of ketoprofen tablets were prepared using the extracted starch as binder in varying proportions. The tablets were prepared by wet granulation technique. Pre compression and post compression parameters were performed for all the prepared formulation batches. The prepared tablets showed good friability and hardness which are within the limits. The drug content of the formulations was found to be in the range of 94 to 96%. Formulation F2 showed better results as compared to other formulations in terms of disintegration test and in-vitro dissolution studies. The results obtained in this study confirmed that starch isolated from Lentil, a natural source is having an excellent binding property which could be employed as an alternate excipient in the routine manufacturing of tablet dosage form.
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